UROP Research Mentor Project Submission Portal: Submission #1247
Submission information
              Submission Number: 1247
  Submission ID: 20831
  Submission UUID: d80585b3-8473-4615-a84b-a5b403bceeee
      Submission URI: /urop-research-mentor-project-submission-portal
          Submission Update: /urop-research-mentor-project-submission-portal?token=3QdQmF4LJmLcov2nw4bk-1Sxyvz6rp-0DU5ZT3rbub4
      Created: Mon, 08/18/2025 - 02:43 PM
  Completed: Mon, 08/18/2025 - 02:43 PM
  Changed: Mon, 09/15/2025 - 11:59 AM
  Remote IP address: 144.174.212.38
  Submitted by: Anonymous
  Language: English
  Is draft: No
    Webform: UROP Project Proposal Portal
      Submitted to: UROP Research Mentor Project Submission Portal
    
          Research Mentor Information
      
  
  
  Rhiannon Crawford
  
  
  
  
      
  
  
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  Graduate Student
  
  
  
  
      
  
  
  Christopher Solís
  
  
  
  
  
      
  
  
  Education, Health, and Human Sciences
  
  
  
  
      
  
  
  Health, Nutrition, and Food Sciences
  
  
  
  
      
  
  
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          Additional Research Mentor(s)
      
  
  
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          Overall Project Details
      
  
  
  Analysis of sarcomeres in cardiac muscle cells by AI software SarcAsM
  
  
  
  
      
  
  
  Bioengineering and biomedical engineering, Computational Science, Biological Sciences, Sarcomeric proteins
  
  
  
  
      
  
  
  No
  
  
  
  
      
  
  
  1
  
  
  
  
      
  
  
  Computational biology, engineering, biomedical engineering, computer science
  
  
  
  
      
  
  
  On FSU Main Campus
  
  
  
  
      
  
  
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  Partially Remote
  
  
  
  
      
  
  
  4-10
  
  
  
  
      
  
  
  Flexible schedule (Combination of business and outside of business. TBD between student and research mentor.)
  
  
  
  
      
  
  
  α-actinin-2 (ACTN2) is a protein in the actin-binding domain (ABD) within the Z-discs of sarcomeres, and helps maintain the structure and function of muscle fibers, which perform contractions. Some cardiac muscle diseases, like hypertrophic cardiomyopathy (HCM), occur due to genetic mutations that regulate function. This project will analyze how different mutations affect sarcomere assembly/growth. The main goal of this project is to quantify sarcomere assembly using an AI software that assesses multilevel structures and functions of sarcomeres and cardiomyocytes.
  
  
  
  
      
  
  
  Literature review, data collection and analysis (coding, programming data), statistical analysis, graph-making
  
  
  
  
      
  
  
  Good computer skills and experience with statistical analysis. Experience/knowledge in programming and coding, using data tools like Python.
  
  
  
  
      
  
  
  I believe my role as a mentor is to encourage scientific curiosity, excitement, and resilience in young scientists. I view mentorship as a collaborative relationship with aims to cultivate critical thinking and problem-solving with room for error and learning opportunities for both me and mentees. By promoting open communication, support, and a light-hearted environment, I hope to empower mentees to confidently pursue science and their long-term goals.
  
  
  
  
      
  
  
  https://solislab.create.fsu.edu/                  https://scholar.google.com/citations?hl=en&user=1YgAo_sAAAAJ
  
  
  
  
      
  
  
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UROP Program Elements
      
  
  
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  2025
  
  
  
  
      
  
  
  https://cre.fsu.edu/urop-research-mentor-project-submission-portal?token=3QdQmF4LJmLcov2nw4bk-1Sxyvz6rp-0DU5ZT3rbub4