UROP Research Mentor Project Submission Portal: Submission #1247

Submission information
Submission Number: 1247
Submission ID: 20831
Submission UUID: d80585b3-8473-4615-a84b-a5b403bceeee

Created: Mon, 08/18/2025 - 02:43 PM
Completed: Mon, 08/18/2025 - 02:43 PM
Changed: Mon, 09/15/2025 - 11:59 AM

Remote IP address: 144.174.212.38
Submitted by: Anonymous
Language: English

Is draft: No

Research Mentor Information

Rhiannon Crawford
She/her
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rqc18@fsu.edu
Graduate Student
Christopher Solís
csolis@fsu.edu
Education, Health, and Human Sciences
Health, Nutrition, and Food Sciences
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Additional Research Mentor(s)

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Overall Project Details

Analysis of sarcomeres in cardiac muscle cells by AI software SarcAsM
Bioengineering and biomedical engineering, Computational Science, Biological Sciences, Sarcomeric proteins
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Computational biology, engineering, biomedical engineering, computer science
On FSU Main Campus
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Partially Remote
4-10
Flexible schedule (Combination of business and outside of business. TBD between student and research mentor.)
α-actinin-2 (ACTN2) is a protein in the actin-binding domain (ABD) within the Z-discs of sarcomeres, and helps maintain the structure and function of muscle fibers, which perform contractions. Some cardiac muscle diseases, like hypertrophic cardiomyopathy (HCM), occur due to genetic mutations that regulate function. This project will analyze how different mutations affect sarcomere assembly/growth. The main goal of this project is to quantify sarcomere assembly using an AI software that assesses multilevel structures and functions of sarcomeres and cardiomyocytes.
Literature review, data collection and analysis (coding, programming data), statistical analysis, graph-making
Good computer skills and experience with statistical analysis. Experience/knowledge in programming and coding, using data tools like Python.
I believe my role as a mentor is to encourage scientific curiosity, excitement, and resilience in young scientists. I view mentorship as a collaborative relationship with aims to cultivate critical thinking and problem-solving with room for error and learning opportunities for both me and mentees. By promoting open communication, support, and a light-hearted environment, I hope to empower mentees to confidently pursue science and their long-term goals.
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UROP Program Elements

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2025
https://cre.fsu.edu/urop-research-mentor-project-submission-portal?token=3QdQmF4LJmLcov2nw4bk-1Sxyvz6rp-0DU5ZT3rbub4