UROP Research Mentor Project Submission Portal: Submission #1219

Research Mentor Information
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Primary Research Mentor Name: Yanchang Wang
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Contact Email (FSU Email if affiliated): yanchang.wang@med.fsu.edu
Position Title: Faculty
FSU College (if applicable): Medicine
FSU Department or Non-FSU Organization Affiliation: Biomedical Sciences
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Additional Research Mentor(s)
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Research Assistant Supervisor (if different from above): Sophia Owutey
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Overall Project Details
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Title of the Project: The role of SUMOylation in cell cycle
Project Keywords: Investigate how SUMOylation of DNA damage repair proteins facilitates damage repair and maintain genome stability, a key mechanism preventing cancer development.
Are you currently looking for research assistants?: Maybe one more
Number of Research Assistants Needed : 1
Relevant Research Assistant Major(s):
Biology, chemistry.

Project Location:: On FSU Main Campus
If the project location is off campus, does the research assistant(s) need to provide their own transportation?: {Empty}
Please select the choice that most accurately describes your expectations for the research assistant(s):: In-person
Approximately how many hours a week would the research assistant(s) need to work?: 10
Roughly what time frame do you expect research assistant(s) to work?: During business hours
Overall Research Project Description:
DNA damage repair is essential to maintain genome stability and prevent cancer development. SUMOylation is a posttranslational modification, and many DNA damage repair proteins are SUMOylated. However, the function of this protein modification in DNA damage repair remains unclear. This project will use molecular, genetic, and imaging methods to understand how SUMOylation controls the localization of DNA damage repair proteins at damage sites to facilitate damage repair. Results from this project will reveal new mechanisms to maintain genome stability.

Research Tasks:
yeast strain construction, imaging with fluorescence microscope, protein analysis using western blotting, media preparation.

Skills that research assistant(s) may need::
recommended: basic background knowledge in cell biology and genetics.

Mentoring Philosophy:
My mentoring philosophy centers on training critical thinking. Beyond technical skills, I encourage trainees to ask meaningful questions, evaluate evidence, and consider alternative interpretations. I aim to provide guidance while fostering independence, helping mentees take ownership of their projects and defend their ideas. By cultivating curiosity, resilience, and intellectual rigor, I seek to prepare trainees not only as capable researchers but also as adaptable problem-solvers who can contribute creatively in any career path.

Please provide a link to your publications, a video clip, or a website for your research project (if applicable):: https://public.med.fsu.edu/com/directory/Details/Full/10841?directoryId=10841
Please add any additional information here (if applicable)::
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Are you interested in participating in the UROP Research Mentor Roundtable?: No
Roundtable times and Zoom links:
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UROP Program Elements
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Mentor Handbook, FAQs, and Communication: Yes
UROP Performance Evaluation: Yes
Materials Grant: Yes
UROP Poster Presentation: Yes

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Year: 2025
update url: https://cre.fsu.edu/urop-research-mentor-project-submission-portal?token=XZmLYX5g-lOgSyqiPZ43Rpufj_uIRo0no64JydxF3LI