UROP Research Mentor Project Submission Portal: Submission #1219 | Center for Undergraduate Research and Academic Engagement

Submission information

Submission Number: 1219

Submission ID: 20691

Submission UUID: 6d0a8b68-2edf-4667-ac93-05d42fba0dba

Submission URI: /urop-research-mentor-project-submission-portal

Submission Update: /urop-research-mentor-project-submission-portal?token=XZmLYX5g-lOgSyqiPZ43Rpufj_uIRo0no64JydxF3LI

Created: Mon, 08/18/2025 - 09:58 AM

Completed: Mon, 08/18/2025 - 09:58 AM

Changed: Mon, 08/25/2025 - 12:39 PM

Remote IP address: 128.186.169.71

Submitted by: Anonymous

Language: English

Is draft: No

Webform: UROP Project Proposal Portal

Submitted to: UROP Research Mentor Project Submission Portal

Research Mentor Information

Primary Research Mentor Name Yanchang Wang

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Contact Email (FSU Email if affiliated) yanchang.wang@med.fsu.edu

Position Title Faculty

FSU College (if applicable) Medicine

FSU Department or Non-FSU Organization Affiliation Biomedical Sciences

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Additional Research Mentor(s)

Research Assistant Supervisor (if different from above) Sophia Owutey

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Overall Project Details

Title of the Project The role of SUMOylation in cell cycle

Project Keywords Investigate how SUMOylation of DNA damage repair proteins facilitates damage repair and maintain genome stability, a key mechanism preventing cancer development.

Are you currently looking for research assistants? Maybe one more

Number of Research Assistants Needed 1

Relevant Research Assistant Major(s) Biology, chemistry.

Project Location: On FSU Main Campus

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Please select the choice that most accurately describes your expectations for the research assistant(s): In-person

Approximately how many hours a week would the research assistant(s) need to work? 10

Roughly what time frame do you expect research assistant(s) to work? During business hours

Overall Research Project Description DNA damage repair is essential to maintain genome stability and prevent cancer development. SUMOylation is a posttranslational modification, and many DNA damage repair proteins are SUMOylated. However, the function of this protein modification in DNA damage repair remains unclear. This project will use molecular, genetic, and imaging methods to understand how SUMOylation controls the localization of DNA damage repair proteins at damage sites to facilitate damage repair. Results from this project will reveal new mechanisms to maintain genome stability.

Research Tasks yeast strain construction, imaging with fluorescence microscope, protein analysis using western blotting, media preparation.

Skills that research assistant(s) may need: recommended: basic background knowledge in cell biology and genetics.

Mentoring Philosophy My mentoring philosophy centers on training critical thinking. Beyond technical skills, I encourage trainees to ask meaningful questions, evaluate evidence, and consider alternative interpretations. I aim to provide guidance while fostering independence, helping mentees take ownership of their projects and defend their ideas. By cultivating curiosity, resilience, and intellectual rigor, I seek to prepare trainees not only as capable researchers but also as adaptable problem-solvers who can contribute creatively in any career path.

Please provide a link to your publications, a video clip, or a website for your research project (if applicable): https://public.med.fsu.edu/com/directory/Details/Full/10841?directoryId=10841

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Are you interested in participating in the UROP Research Mentor Roundtable? No

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UROP Program Elements

Mentor Handbook, FAQs, and Communication Yes

UROP Performance Evaluation Yes

Materials Grant Yes

UROP Poster Presentation Yes

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Year 2025

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