UROP Research Mentor Project Submission Portal: Submission #1219
Submission information
              Submission Number: 1219
  Submission ID: 20691
  Submission UUID: 6d0a8b68-2edf-4667-ac93-05d42fba0dba
      Submission URI: /urop-research-mentor-project-submission-portal
          Submission Update: /urop-research-mentor-project-submission-portal?token=XZmLYX5g-lOgSyqiPZ43Rpufj_uIRo0no64JydxF3LI
      Created: Mon, 08/18/2025 - 09:58 AM
  Completed: Mon, 08/18/2025 - 09:58 AM
  Changed: Wed, 10/29/2025 - 03:48 PM
  Remote IP address: 128.186.169.71
  Submitted by: Anonymous
  Language: English
  Is draft: No
    Webform: UROP Project Proposal Portal
      Submitted to: UROP Research Mentor Project Submission Portal
    
          | Primary Research Mentor Name | Yanchang Wang | 
|---|---|
| Research Mentor Preferred Pronouns | |
| When potential research assistants are reaching out via email, what is your preferred honorific? | |
| Contact Email (FSU Email if affiliated) | yanchang.wang@med.fsu.edu | 
| Position Title | Faculty | 
| FSU College (if applicable) | Medicine | 
| FSU Department or Non-FSU Organization Affiliation | Biomedical Sciences | 
| Headshot (optional) | |
| Research Assistant Supervisor (if different from above) | Sophia Owutey | 
| Research Assistant Supervisor Preferred Pronouns | |
| Research Assistant Supervisor Preferred Honorific? | |
| Contact Email (FSU Email if affiliated) | |
| Name of Other Faculty/Collaborator(s) (if applicable) | |
| Other Faculty/Collaborator(s) Preferred Pronouns | |
| Other Faculty/Collaborator(s) Preferred Honorific? | |
| Contact Email (FSU Email if affiliated) | |
| Title of the Project | The role of SUMOylation in cell cycle | 
| Project Keywords | Investigate how SUMOylation of DNA damage repair proteins facilitates damage repair and maintain genome stability, a key mechanism preventing cancer development. | 
| Are you currently looking for research assistants? | No | 
| Number of Research Assistants Needed | 1 | 
| Relevant Research Assistant Major(s) | Biology, chemistry. | 
| Project Location: | On FSU Main Campus | 
| If the project location is off campus, does the research assistant(s) need to provide their own transportation? | |
| Please select the choice that most accurately describes your expectations for the research assistant(s): | In-person | 
| Approximately how many hours a week would the research assistant(s) need to work? | 10 | 
| Roughly what time frame do you expect research assistant(s) to work? | During business hours | 
| Overall Research Project Description | DNA damage repair is essential to maintain genome stability and prevent cancer development. SUMOylation is a posttranslational modification, and many DNA damage repair proteins are SUMOylated. However, the function of this protein modification in DNA damage repair remains unclear. This project will use molecular, genetic, and imaging methods to understand how SUMOylation controls the localization of DNA damage repair proteins at damage sites to facilitate damage repair. Results from this project will reveal new mechanisms to maintain genome stability. | 
| Research Tasks | yeast strain construction, imaging with fluorescence microscope, protein analysis using western blotting, media preparation. | 
| Skills that research assistant(s) may need: | recommended: basic background knowledge in cell biology and genetics. | 
| Mentoring Philosophy | My mentoring philosophy centers on training critical thinking. Beyond technical skills, I encourage trainees to ask meaningful questions, evaluate evidence, and consider alternative interpretations. I aim to provide guidance while fostering independence, helping mentees take ownership of their projects and defend their ideas. By cultivating curiosity, resilience, and intellectual rigor, I seek to prepare trainees not only as capable researchers but also as adaptable problem-solvers who can contribute creatively in any career path. | 
| Please provide a link to your publications, a video clip, or a website for your research project (if applicable): | https://public.med.fsu.edu/com/directory/Details/Full/10841?directoryId=10841 | 
| Please add any additional information here (if applicable): | |
| Are you interested in participating in the UROP Research Mentor Roundtable? | No | 
| Roundtable times and Zoom links | |
| Mentor Handbook, FAQs, and Communication | Yes | 
| UROP Performance Evaluation | Yes | 
| Materials Grant | Yes | 
| UROP Poster Presentation | Yes | 
| Year | 2025 | 
| update url | https://cre.fsu.edu/urop-research-mentor-project-submission-portal?token=XZmLYX5g-lOgSyqiPZ43Rpufj_uIRo0no64JydxF3LI |