UROP Research Mentor Project Submission Portal: Submission #1013 | Center for Undergraduate Research and Academic Engagement

Submission information

Submission Number: 1013

Submission ID: 19661

Submission UUID: 66658efb-89a8-4778-be80-8c0faec2548d

Submission URI: /urop-research-mentor-project-submission-portal

Submission Update: /urop-research-mentor-project-submission-portal?token=3pN6_h1prrWJYTGWnXNgZW1F8rtRpBTdFHNQkRflP3g

Created: Tue, 05/27/2025 - 06:31 PM

Completed: Tue, 05/27/2025 - 06:31 PM

Changed: Wed, 10/29/2025 - 12:37 PM

Remote IP address: 217.180.196.28

Submitted by: Anonymous

Language: English

Is draft: No

Webform: UROP Project Proposal Portal

Submitted to: UROP Research Mentor Project Submission Portal

Research Mentor Information

Primary Research Mentor Name Yan Li

Research Mentor Preferred Pronouns Dr. Li

When potential research assistants are reaching out via email, what is your preferred honorific? Dr.

Contact Email (FSU Email if affiliated) yli@eng.famu.fsu.edu

Position Title Faculty

FSU College (if applicable) FAMU-FSU College of Engineering

FSU Department or Non-FSU Organization Affiliation Florida State University

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Additional Research Mentor(s)

Research Assistant Supervisor (if different from above) Colin Esmonde

Research Assistant Supervisor Preferred Pronouns {Empty}

Research Assistant Supervisor Preferred Honorific? {Empty}

Contact Email (FSU Email if affiliated) cme18b@fsu.edu

Name of Other Faculty/Collaborator(s) (if applicable) {Empty}

Other Faculty/Collaborator(s) Preferred Pronouns {Empty}

Other Faculty/Collaborator(s) Preferred Honorific? {Empty}

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Overall Project Details

Title of the Project Chimeric antigen receptor engineered extracellular vesicle delivery for treating neurological disorders

Project Keywords extracellular vesicles, human stem cells, 3-D culture, neural engineering

Are you currently looking for research assistants? No

Number of Research Assistants Needed 1

Relevant Research Assistant Major(s) Biomedical Engineering

Project Location: 2525 Pottsdamer St., Tallahassee, FL

If the project location is off campus, does the research assistant(s) need to provide their own transportation? Yes

Please select the choice that most accurately describes your expectations for the research assistant(s): Partially Remote

Approximately how many hours a week would the research assistant(s) need to work? 5-10

Roughly what time frame do you expect research assistant(s) to work? During business hours

Overall Research Project Description Immune therapy has proven to be an effective method of targeting FAP overexpressing cells for lysis, especially in cancer research. By using engineered chimeric antigen receptors (CARs), patient immune cells can be programmed to target tumor and tumor- associated antigens, eliciting a strong inflammatory response that is difficult for tumors to suppress. T-cells engineered to express CARs that target FAP localize to the tumor microenvironment, destroying fibroblasts in the tumor stroma that mediate immune suppression and cause tumor- associated fibrosis.

Research Tasks literature review, data collection, data analysis,

Skills that research assistant(s) may need: cell culture, reading and writing skills,

Mentoring Philosophy I mainly focus on the self-motivation driven research. I will identify the students' motivation and motivate them more. I help and encourage students to pay attention to small details and put deep thoughts while performing experiments. When students gain more understanding and skills, I challenge them to develop independent thoughts. I also share my own experience. I create a safe environment in which mentees feel that is acceptable to fail and learn from their mistakes.

Please provide a link to your publications, a video clip, or a website for your research project (if applicable): https://scholar.google.com/citations?user=hHCTRMgAAAAJ&hl=en

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Are you interested in participating in the UROP Research Mentor Roundtable? Yes

Roundtable times and Zoom links Sep 03, 2:00pm-2:30pm
Join Zoom Meeting
https://fsu.zoom.us/j/92174327545
Meeting ID: 921 7432 7545

Roundtable Info

Day: Wednesday, September 3
Start Time: 2:00
End Time: 2:30
Zoom Link: https://fsu.zoom.us/j/92174327545 Meeting ID: 921 7432 7545

UROP Program Elements

Mentor Handbook, FAQs, and Communication Yes

UROP Performance Evaluation Yes

Materials Grant Yes

UROP Poster Presentation Yes

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Year 2025

update url https://cre.fsu.edu/urop-research-mentor-project-submission-portal?token=3pN6_h1prrWJYTGWnXNgZW1F8rtRpBTdFHNQkRflP3g