UROP Research Mentor Project Submission Portal: Submission #686

Submission information
Submission Number: 686
Submission ID: 14051
Submission UUID: b38027bc-04e7-43b8-945a-0e2d3e6c2101

Created: Fri, 07/19/2024 - 03:40 PM
Completed: Fri, 07/19/2024 - 04:40 PM
Changed: Thu, 09/12/2024 - 12:29 PM

Remote IP address: 128.186.175.157
Submitted by: Anonymous
Language: English

Is draft: No
Primary Research Mentor Name Yanchang Wang
Research Mentor Preferred Pronouns
When potential research assistants are reaching out via email, what is your preferred honorific?
Contact Email (FSU Email if affiliated) yanchang.wang@med.fsu.edu
Position Title Faculty
FSU College (if applicable) Medicine
FSU Department or Non-FSU Organization Affiliation Biomedical Sciences
Headshot (optional) Wang-15.jpg
Research Assistant Supervisor (if different from above)
Research Assistant Supervisor Preferred Pronouns
Research Assistant Supervisor Preferred Honorific?
Contact Email (FSU Email if affiliated)
Name of Other Faculty/Collaborator(s) (if applicable)
Other Faculty/Collaborator(s) Preferred Pronouns
Other Faculty/Collaborator(s) Preferred Honorific?
Contact Email (FSU Email if affiliated)
Title of the Project A new mechanism that controls protein subcellular localization and function
Project Keywords protein SUMOylation, polySUMOylation, cell cycle, protein misfolding
Are you currently looking for research assistants? No
Number of Research Assistants Needed 2
Relevant Research Assistant Major(s) Biology, Biochemistry
Project Location: On FSU Main Campus
If the project location is off campus, does the research assistant(s) need to provide their own transportation?
Please select the choice that most accurately describes your expectations for the research assistant(s): In-person
Approximately how many hours a week would the research assistant(s) need to work? 10
Roughly what time frame do you expect research assistant(s) to work? During business hours
Overall Research Project Description Protein subcellualr localization is critical for its cellular function. Recently, our lab uncovered a new mechanism that controls protein subcellular localization through SUMOylation, a process in which SUMO proteins are covalently attached to specific lysine residues in target proteins. SUMOylation is important for stress response, cell cycle, DNA damage repair, and other cellular processes. SUMOylation imbalances can cause cancer and neurodegenerative diseases. The current focus of our lab is to understand how SUMOylation regulates the subcellular localization of key mitotic players and how SUMOylation is regulated during cell cycle.
Research Tasks Yeast strain construction
Molecular method to detect protein expression and modification
Cell imaging
Skills that research assistant(s) may need: Cell culture, microscopy
Mentoring Philosophy As an educator, I will enable students to learn some basic technology in genetics and cell biology by performing experiments, to receive training in critical thinking through the interaction with mentor and other lab members, to improve communication skills by presenting his/her own research work.
Please provide a link to your publications, a video clip, or a website for your research project (if applicable): https://www.sciencedirect.com/science/article/pii/S2211124724008210?via%3Dihub
Please add any additional information here (if applicable):
Are you interested in participating in the UROP Research Mentor Roundtable? Yes
Roundtable times and Zoom links Roundtable times and Zoom link: Friday, September 6, 2:00-3:00pm. This is drop-in style.
https://fsu.zoom.us/j/92708842643
Roundtable Info
Mentor Handbook, FAQs, and Communication Yes
UROP Performance Evaluation Yes
Materials Grant Yes
UROP Poster Presentation Yes
Year 2024
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