UROP Research Mentor Project Submission Portal: Submission #1358
Submission information
Submission Number: 1358
Submission ID: 21386
Submission UUID: 1d3d27ba-1592-464a-a70c-83504b30379e
Submission URI: /urop-research-mentor-project-submission-portal
Submission Update: /urop-research-mentor-project-submission-portal?token=-2xPxwIPFBTpdkgoCzgchafMrLVUKWBAdASaCpUG26M
Created: Thu, 09/04/2025 - 02:42 PM
Completed: Thu, 09/04/2025 - 03:58 PM
Changed: Fri, 09/05/2025 - 10:43 AM
Remote IP address: 144.174.212.123
Submitted by: Anonymous
Language: English
Is draft: No
Webform: UROP Project Proposal Portal
Submitted to: UROP Research Mentor Project Submission Portal
serial: '1358' sid: '21386' uuid: 1d3d27ba-1592-464a-a70c-83504b30379e uri: /urop-research-mentor-project-submission-portal created: '1757011329' completed: '1757015926' changed: '1757083398' in_draft: '0' current_page: '' remote_addr: 144.174.212.123 uid: '0' langcode: en webform_id: urop_project_proposal_portal entity_type: node entity_id: '1116' locked: '0' sticky: '0' notes: '' metatag: meta data: roundtable_info: { } approximately_how_many_hours_a_week_would_the_research_assistant: '10' are_you_currently_looking_for_students_: 'Yes' confirmation_1: '1' contact_email_fsu_email: '' contact_email_fsu_email2: '' contact_email_fsu_email_if_affiliated_: jb25bw@fsu.edu faculty_advisor_confirmation: '' faculty_advisor_name: '' faculty_advisor_s_fsu_email: '' fsu_college: 'Education, Health, and Human Sciences' fsu_department_if_applicable_: 'Health, Nutrition, and Food Sciences' headshot_optional_: '63346' if_the_project_location_is_off_campus_does_the_student_need_to_p: 'Yes' mentoring_philosophy: 'The best experience that I have had when I was a mentee was when I sat down with my mentor, and we both discussed different directions to take a project during my first year of graduate school. My mentor listened to my ideas, and we ended up creating a plan to finish the project. This mentoring approach helped me publish a first author manuscript. My graduate school mentor focused on listening to me, helping me critically think about topics, and planning to achieve my goals. I have applied a similar approach when mentoring students and technicians. Each student/technician I have mentored, I have applied a mix of hands-on approaches as well as teaching the information in a casual manner. I believe the mentoring skills I have acquired are applicable to the classroom setting. I will make scheduled times to mentor and advise my students that I teach in the classroom. I will focus on communication and building relationships with the individual.' mentor_handbook_and_faqs: '1' name_of_other_faculty_collaborator_if_applicable_: '' number_of_assistants_needed_faculty_postdoc_max_6_graduate_stude: '6' other_faculty_collaborator_s_preferred_pronouns: '' overall_research_project_description: |- Cancer cachexia is a muscle wasting syndrome that occurs in ~80% of cancer patients and is the primary cause of death for 22%-30% of cancer patients. Cancer cachexia patients are unlikely to benefit from physical therapies designed to increase muscle mass and function. The primary challenge associated with cancer cachexia is that effective therapies to treat the associated muscle loss and dysfunction are lacking. Research exploring whether reactive oxygen species (ROS i.e. superoxide anion and hydrogen peroxide) contributes to cancer cachexia has had mixed results. Lipid peroxidation is an underexplored component of oxidative stress that may contribute to cancer cachexia as markers of lipid peroxidation such as 4-hydroxyneoneal (4-HNE) and MDA (Malondialdehyde) are higher in muscle from tumor-bearing mice when compared to controls. Phospholipid hydroperoxide glutathione peroxidase (GPx4) is an antioxidant enzyme that reduces lipid hydroperoxides. We hypothesized that reducing lipid peroxidation via GPx4 overexpression would mitigate cancer cachexia in tumor-bearing mice. please_add_any_additional_information_here: '' please_provide_a_link_to_your_publications_a_video_clip_or_a_web: 'https://annescollege.fsu.edu/faculty-staff/dr-jacob-brown' please_select_the_choice_that_most_accurately_describes_your_exp: In-person please_select_the_location_of_your_project_: 'On FSU Main Campus' position_availability_for_student_research: 'Flexible schedule' position_title: Faculty primary_research_mentor_name: 'Jacob Brown' project_keywords: 'Skeletal Muscle, Cancer, Diabetes, Metabolism' relevant_student_major_s_: 'Open to all majors' research_mentor_preferred_pronoun2: '' research_mentor_pronouns: '' research_mentor_supervisor_if_different_from_above_: '' research_tasks_for_student_research_assistant_s_: |- -Literature review -Data analysis -Data collection roundtable_times_and_zoom_links: '' skills_that_research_assistants_may_need_: |- Required: Excellent communication skills and the ability to work as a team. Recommended: Pipetting title_of_the_project: 'The role of oxylipins in skeletal muscle atrophy' update_url: 'https://cre.fsu.edu/urop-research-mentor-project-submission-portal?element_parents=elements/research_mentor_information/headshot_optional_&ajax_form=1&_wrapper_format=drupal_ajax&token=-2xPxwIPFBTpdkgoCzgchafMrLVUKWBAdASaCpUG26M' urop_performance_evaluation: '1' urop_poster_presentation: '1' when_potential_research_assistants_are_reaching_out_via_email_2: '' when_potential_research_assistants_are_reaching_out_via_email_wh: '' when_students_are_reaching_out_via_email_what_is_your_preferreda: '' would_you_like_to_participate_in_the_urop_research_mentor_round2: 'No' would_you_like_to_participate_in_the_urop_research_mentor_roundt: '' year: '2025'