UROP Research Mentor Project Submission Portal: Submission #1140

serial: '1140'
sid: '20296'
uuid: f07abdb7-f42b-4bf9-b4ce-04276eb79a60
uri: /urop-research-mentor-project-submission-portal
created: '1755137581'
completed: '1755137605'
changed: '1756143007'
in_draft: '0'
current_page: ''
remote_addr: 68.59.110.70
uid: '0'
langcode: en
webform_id: urop_project_proposal_portal
entity_type: node
entity_id: '1116'
locked: '0'
sticky: '0'
notes: ''
metatag: meta
data:
  roundtable_info: {  }
  approximately_how_many_hours_a_week_would_the_research_assistant: '10'
  are_you_currently_looking_for_students_: 'Yes'
  confirmation_1: '1'
  contact_email_fsu_email: ''
  contact_email_fsu_email2: ''
  contact_email_fsu_email_if_affiliated_: dlee@eng.famu.fsu.edu
  faculty_advisor_confirmation: ''
  faculty_advisor_name: ''
  faculty_advisor_s_fsu_email: ''
  fsu_college: 'FAMU-FSU College of Engineering'
  fsu_department_if_applicable_: 'Chemical and Biomedical Engineering'
  headshot_optional_: ''
  if_the_project_location_is_off_campus_does_the_student_need_to_p: 'there is public transportation, via FSU shuttle to innovation park'
  mentoring_philosophy: 'As the most of the undergraduates are new to research and will face various challenges. I will establish various communication channels with the undergraduate to ensure that the student can communicate with me whenever an issue arises even outside of our scheduled meetings. This will be especially critical at the beginning when the student faces a completely new topic and learns new approaches. By creating such environment, I believe the student will feel supported and encouraged to ask critical questions for the success of the project and the student.'
  mentor_handbook_and_faqs: '1'
  name_of_other_faculty_collaborator_if_applicable_: ''
  number_of_assistants_needed_faculty_postdoc_max_6_graduate_stude: '1'
  other_faculty_collaborator_s_preferred_pronouns: ''
  overall_research_project_description: 'After spontaneous protein phase separation (PS) in a living cell was observed for the first time, subsequent studies have revealed that the occurrence of biomolecular PS is ubiquitous in a living system. The immediate consequence of PS is the formation of membraneless organelles (MLOs), where select biomolecules such as proteins and mRNAs are enriched. Due to such enrichment of selective biomolecules, MLOs are suggested to play important regulatory roles in cellular processes. Past studies focused on biophysical mechanisms behind the biomolecular PS, which significantly enhances our understanding of the PS processes. Despite such progress in the past decade, we lack a predictive model that accurately predicts the dynamics of MLO formation in living cells. Motivated by the above considerations, this project aims to 1) construct a mechanistic model that describes the dynamics of MLO formation in bacteria  2) perform estimation of parameters in the proposed model to maximize the predictive capability of the proposed model based on the real microscopic images of MLOs in bacteria 3) Validate the prediction accuracy by performing new experiments (in bacteria).'
  please_add_any_additional_information_here: 'If anyone is interested in knowing more about the project, please send me an email to schedule a meeting. '
  please_provide_a_link_to_your_publications_a_video_clip_or_a_web: 'https://scholar.google.com/citations?user=RWaEOVgAAAAJ&hl=en'
  please_select_the_choice_that_most_accurately_describes_your_exp: 'Partially Remote'
  please_select_the_location_of_your_project_: 'Interdisciplinary Research and Commercialization Building ,2001 Levy Avenue'
  position_availability_for_student_research: 'Flexible schedule'
  position_title: Faculty
  primary_research_mentor_name: 'Dongheon Lee'
  project_keywords: 'synthetic biology, mathematical modeling, molecular biology'
  relevant_student_major_s_: 'Engineering, Chemistry, Biochemistry, Biology, Physics, Math, Computational Science or any other relevant major'
  research_mentor_preferred_pronoun2: ''
  research_mentor_pronouns: ''
  research_mentor_supervisor_if_different_from_above_: ''
  research_tasks_for_student_research_assistant_s_: |-
    Literature Review, Simulation Submissions on RCC Cluster, Data Collection, Data Analysis, Scientific Writing, and Presentation
    if the simulation part goes well, students will perform fluorescence microscopy experiments to image the formation of membraneless organelles in bacteria
  roundtable_times_and_zoom_links: ''
  skills_that_research_assistants_may_need_: |-
    Required: Willingness to learn, Computer competency, Scientific curiosity
    Recommended: Prior coding knowledge, Basic knowledge of molecular biology
  title_of_the_project: 'Studying dynamics of membraneless organelles formation in living cells  through computational modeling '
  update_url: 'https://cre.fsu.edu/urop-research-mentor-project-submission-portal?token=8HhvkXSncj8JbDNPDUeiCTG-MVOu7-SIYGRP2hVIKrM'
  urop_performance_evaluation: '1'
  urop_poster_presentation: '1'
  when_potential_research_assistants_are_reaching_out_via_email_2: ''
  when_potential_research_assistants_are_reaching_out_via_email_wh: ''
  when_students_are_reaching_out_via_email_what_is_your_preferreda: ''
  would_you_like_to_participate_in_the_urop_research_mentor_round2: 'No'
  would_you_like_to_participate_in_the_urop_research_mentor_roundt: ''
  year: '2025'