Novel models and simulation of bacterial networks and their collective behavior

Quorum sensing, bacterial colonies, systems biology, networks, decision-making, game theory

Research Mentor: Marcos Muller Vasconcelos,
Department, College, Affiliation: Electrical and Computer Engineering , FAMU-FSU College of Engineering
Contact Email: m.vasconcelos@fsu.edu
Research Assistant Supervisor (if different from mentor):
Research Assistant Supervisor Email:
Faculty Collaborators:
Faculty Collaborators Email:

Looking for Research Assistants: Yes
Number of Research Assistants: 2
Relevant Majors: Open to all majors
Project Location: FAMU-FSU College of Engineering
Research Assistant Transportation Required: Yes
Remote or In-person: Partially Remote
Approximate Weekly Hours: 10 hours/week, Flexible schedule (Combination of business and outside of business. TBD between student and research mentor.)
Roundtable Times and Zoom Link: Not participating in the Roundtable

Project Description

Bacteria are among the simplest life forms on Earth. Each bacterial cell possesses minimal sensing and actuation capabilities. Nevertheless, they can perform incredibly complex tasks as if operating in unison, akin to the formation of multicellular organisms. Behind this intriguing phenomenon lies a mechanism known as Quorum Sensing. In this project, students will delve into understanding how Quorum Sensing operates, learn the art of mathematically modeling it, and engage in computer simulations. Additionally, they will gain proficiency in using Cello, a programming language designed for creating computational circuits within living cells.

Research Tasks: Literature review
Learn mathematical modeling of inter and intra species bacterial quorum sensing
Perform Matlab and/or Python simulations
Learn how to use the language Cello to design DNA code for decision-making bacteria



Skills that research assistant(s) may need: Knowledge of Matlab or equivalent (recommended, but not required)
Interest in synthetic biology (strongly recommended)