UROP Project

Spatial Profiling of Chronic Sleep Deprivation Induced Molecular Changes

Sleep, mice, imaging analysis, RNA, protein, neuroscience, hippocampus
Research Mentor: Colton Remedies, he/him
Department, College, Affiliation: Department of Biological Sciences, Arts and Sciences
Contact Email: ceremedies@fsu.edu
Research Assistant Supervisor (if different from mentor):
Research Assistant Supervisor Email:
Faculty Collaborators:
Faculty Collaborators Email:
Looking for Research Assistants: Yes
Number of Research Assistants: 2
Relevant Majors: Neuroscience, Biology, Biochemistry, BMS
Project Location: On FSU Main Campus
Research Assistant Transportation Required:
Remote or In-person: Partially Remote
Approximate Weekly Hours: 10 hours, During business hours
Roundtable Times and Zoom Link:
Not participating in the roundtable

Project Description

Sleep loss is a significant public health concern that affects ~30% of adults globally. Sleep loss induces learning and memory deficits and increases the incidence of cardiovascular, immune, and neuropsychological disorders. We are focusing on the spatial profile of molecular changes occurring within the hippocampus following chronic sleep deprivation. We are looking for undergraduate research assistants to assist with image analysis, characterization and quantification of hippocampal protein and mRNA alterations following chronic sleep deprivation. As time in the lab progresses students may also become involved in molecular and behavioral experiments.

Research Tasks: Data analysis, image analysis, microscopy

Skills that research assistant(s) may need: Strong background in biology. Recommended: Experience with microscopy and data analysis.

Mentoring Philosophy

I aim to cultivate an atmosphere of critical thinking to promote students to engage in scientific discussions regarding the background subject matter, experimental techniques, analytical methods, and all potential interpretations of our experiments. I emphasize exposure to scientific literature pertaining to our lab goals and encourage students to work independently in their analysis of experimental results, problem solve issues as they arise, and to also work collaboratively in the larger context of our lab.

Additional Information


Link to Publications