President's Showcase

Ian Bridges

Poster Presentation, Ballroom D
Ian Bridges headshot.jpg

Steve Madden Undergraduate Research Award
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ORCID

Artificial Intelligence Assisted Medical Research Article Comprehension and Presentation
Supervising Professor: Dr. Guang Wang
Ian Bridges is a pure Mathematics student and the president of Pi Mu Epsilon, the university's premier mathematics fraternity. Ian demonstrates a first-class commitment to research and learning, producing a recreational mathematics paper in his first year at the university. Ian now works with Dr. Xiuwen Liu as a research assistant, now focusing on mathematical problems in artificial intelligence and quantum computing. In the future, Ian hopes to be pursuing his Ph.D in mathematics at the California Institute of Technology. Ian can be found daily at 3pm in MCH216 at the daily math student tea.

Abstract

The constant influx of new medical research poses challenges for both researchers attempting to find and digest relevant articles and non-medical professionals attempting to gather information about diseases and their treatment methods. We present preliminary results on a classification model to determine whether a paper presents original experimental results. A preliminary model is proposed to determine the independent and dependent variable discussed in the aforementioned papers which present original experimental results.

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Connor Krassel

Poster Presentation, Ballroom D
Connor Krassel 1.jpg

Helen Louise Lee Undergraduate Research Award
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ORCID

NADPH Oxidase (NOX) Lowers ROS Concentrations and Stimulates Adipose Tissue Lipolysis in Humans
Supervising Professor: Dr. Robert Hickner
Connor Krassel was born in Melbourne, Florida and is currently a Junior Biological Sciences major. He plans on applying to medical school at the end of his undergraduate years with the goal of studying anesthesiology. He has been working as a research assistant in Dr. Hickner’s lab for over a year in the College of Health and Human sciences and is now excited to share his own research with Riley Hart through the IDEA Grant program.

Abstract

Cardiovascular disease (CVD) has risen to alarming levels and remains the leading cause of death in the United States. One of the early signs of CVD is elevations in reactive oxygen species (ROS). NADPH oxidase (NOX) is the main source of ROS in blood vessels, and increased NOX activity may impact CVD related factors, such as fat mobilization (lipolysis) and blood flow. PURPOSE: The overall objective of this study was to investigate how NOX-derived ROS production affects blood flow and lipolysis. METHODS: Sixteen sedentary females (age: 21 ± 5 years; body mass index: 22.2 ± 3.8 kg/m2 ; body fat: 31.6 ± 6.8 %) participated in this study. Microdialysis and a hyperinsulinemic-euglycemic were performed where ROS production was measured as H2O2 concentrations, adipose tissue microvascular blood flow (ATMBF) as ethanol outflow/inflow ratio, and lipolysis as glycerol. Apocynin (APO; NOX inhibitor) was infused via microdialysis to determine the contributions of NOX. RESULTS: APO perfusion significantly reduced H2O2 (APO: 0.69 ± 0.27 mM; Control: 1.14 ± 0.51 mM, p = < .0001), decreased ATMBF (APO: 0.79 ± 0.14; Control: 0.68 ± 0.14, p = 0.001) and glycerol (APO: 35.87 ± 18.79 mmol/L; Control: 41.48 ± 23.73 mmol/L, p = 0.0476). No effect of state (basal or clamp) by APO interactions were detected (p = > 0.05). CONCLUSIONS: Reductions in NOX produced ROS are accompanied by decreased blood flow and lipolysis rates that are independent of insulin-regulated pathways. These findings have critical implications as NOX produced ROS may increase the risk of CVD.

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Riley Hart

Poster Presentation, Ballroom D
Riley Hart 1.jpg

Steve Madden Undergraduate Research Award
LinkedIn
ORCID

NADPH Oxidase (NOX) Lowers ROS Concentrations and Stimulates Adipose Tissue Lipolysis in Humans
Supervising Professor: Dr. Robert Hickner
Riley Hart is a senior from Pensacola, Florida majoring in Exercise Physiology with minors in Child Development and Biology. After she finishes her undergraduate degree, she intend to pursue a career as a physician assistant. Riley have been involved in research under Dr. Hickner’s Lab studying oxidative stress and vascular health since her sophomore year as a UROP student. Research has been an imperative experience for her undergraduate career and an important piece of her personal and professional development. Additionally, research has provided Riley the opportunity to make impactful contributions to projects aimed at addressing pressing medical issues, reflecting her strong desires to help others and advance the medical field.

Abstract

Cardiovascular disease (CVD) has risen to alarming levels and remains the leading cause of death in the United States. One of the early signs of CVD is elevations in reactive oxygen species (ROS). NADPH oxidase (NOX) is the main source of ROS in blood vessels, and increased NOX activity may impact CVD related factors, such as fat mobilization (lipolysis) and blood flow. PURPOSE: The overall objective of this study was to investigate how NOX-derived ROS production affects blood flow and lipolysis. METHODS: Sixteen sedentary females (age: 21 ± 5 years; body mass index: 22.2 ± 3.8 kg/m2 ; body fat: 31.6 ± 6.8 %) participated in this study. Microdialysis and a hyperinsulinemic-euglycemic were performed where ROS production was measured as H2O2 concentrations, adipose tissue microvascular blood flow (ATMBF) as ethanol outflow/inflow ratio, and lipolysis as glycerol. Apocynin (APO; NOX inhibitor) was infused via microdialysis to determine the contributions of NOX. RESULTS: APO perfusion significantly reduced H2O2 (APO: 0.69 ± 0.27 mM; Control: 1.14 ± 0.51 mM, p = < .0001), decreased ATMBF (APO: 0.79 ± 0.14; Control: 0.68 ± 0.14, p = 0.001) and glycerol (APO: 35.87 ± 18.79 mmol/L; Control: 41.48 ± 23.73 mmol/L, p = 0.0476). No effect of state (basal or clamp) by APO interactions were detected (p = > 0.05). CONCLUSIONS: Reductions in NOX produced ROS are accompanied by decreased blood flow and lipolysis rates that are independent of insulin-regulated pathways. These findings have critical implications as NOX produced ROS may increase the risk of CVD.

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Janeen Green

Poster Presentation, Ballroom D
Janeen Green Headshot.jpg

Dr. Lisa Scott Undergraduate Research Award
LinkedIn
ORCID

Embodying Islamic Communities: Women's Discernment of Identity in Dearborn, Michigan
Supervising Professor: Dr. Joseph Hellweg
A senior double-majoring in Religion and Humanities, Janeen Green is an Honors in the Major student who is passionate about human rights, social justice, and intercultural communication. After studying abroad in London, England during the summer of 2021, Ms. Green returned to Florida State and interned at the Center for Global Engagement as the Administrative Intern for the Global Citizenship Certificate (GCC), which she is currently enrolled in. She later participated in The Fund for American Studies in Washington, D.C. by attending professional development seminars regularly while simultaneously interning at The Well News. Ms. Green became the President of FSU's Religion Club (SORCE) in the Fall of 2022 and is a member of Alliance for Black Women. This past March, Ms. Green attended Johns Hopkins University's Richard Macksey National Undergraduate Humanities Research Symposium to present her research on Black women's passages through European art. She was selected as the College of Arts and Sciences 2023 Humanitarian of the Year and received an Academic Leadership Award.

Abstract

Arab American Muslim women living in Dearborn, Michigan find themselves situated at the intersection of Islam, feminism, and American culture. Faced with ethical challenges in their lives, these women adapt Islam to different contexts in order to make decisions that are responsive to their communities while remaining authentic to themselves. These ethical theorists cultivate a process of discerning the relative priority they give to various influences in their lives and engage in negotiation on them with their families, friends, and their broader communities. They are able to draw on a repertoire of diverse cultural rhetorics available to them to fashion themselves in very diverse ways within the community that may be perceived from the outside world as homogenous and inflexible but are, in fact, not. The Islamic communities in Dearborn reflect the diversity we see in the United States, especially with narratives providing reflection and imitation for Muslim women to exercise their agency in various spaces. Interviews with civil rights attorneys, human rights advocates, religious leaders, and academics were conducted over four weeks through open-ended, semi-structured interviews and focused life-history interviews. One small focus group also occurred and consisted of Yemeni American Muslim women which enabled them to share their thoughts on key themes that arise in the overlap between Islam and women's flourishing. As home to the largest Muslim population in the United States, Dearborn, Michigan allowed the researcher to immerse within the Arab world as conditions in the Middle East prevented any research to occur.

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