Research Symposium

BIO

My name is Karina Thiyagarajan, and I am studying Biological Sciences on the pre-med track. I am passionate about research in health disparities and public health. In my free time, I enjoy painting. In the future, I hope to become a physician and provide care to diverse communities.

Impact of Chronic Conditions on COVID-19 Vaccine Hesitancy in Individuals with Alzheimer’s Disease

Abstract

COVID-19 vaccination plays a crucial role in preventing severe illness, especially among individuals with Alzheimer’s disease and related dementias (ADRD). Despite the vaccine's effectiveness, hesitancy remains a challenge, particularly among those with chronic conditions like diabetes, hypertension, and heart failure. While previous research has explored vaccine hesitancy in neurological disorders, the impact of coexisting chronic conditions on vaccine acceptance in ADRD populations is less understood. This study examines the link between chronic conditions and vaccine hesitancy using data from the All of Us research program, comparing both ADRD and non-ADRD groups. Participants were categorized based on ADRD status, presence of chronic conditions, and vaccine hesitancy, which was assessed through categories of protection duration. Chi-square tests revealed statistically significant associations between chronic conditions and vaccine hesitancy, with diabetes and heart failure showing the strongest effects. Individuals with ADRD showed greater overall vaccine hesitancy, particularly when dealing with multiple chronic conditions. These findings suggest that chronic health conditions may contribute to vaccine hesitancy in individuals with ADRD. Understanding these factors could inform public health strategies and interventions to increase vaccine uptake in this population. Future research should explore the underlying causes of vaccine hesitancy in ADRD individuals and develop strategies to improve vaccination rates through evidence-based approaches.

Keywords: Vaccine Hesitancy, ADRD, COVID-19 Vaccination