BIO

My name is Dev Sangha and I am from Jersey City, New Jersey. I have an interest in design and research. At the Solis lab, I have the opportunity to merge research with design through the making of a myocardial slice device. I would love to be a surgeon in the future.

Development of Myocardial Slices for Cardiovascular Studies

Abstract

Heart disease and failure remain the top causes of death in the world, even with the many new advancements in the field. Gaining a deeper understanding of the heart can prove to be beneficial for saving lives. Myocardial slices, which are cut to 1 centimeter square and 100 to 400 µ thin, are slices of living muscle tissue from the heart. For testing, the slices are cut from animal hearts. The myocardial strips are then examined, looking at the contractile function of the heart as the living slices contract and expand. A literature review identified the best-suited platform to induce mechanical stimulation onto myocardial sheets. This system is anticipated to support multi-sensory analysis of myocardial tissue response to stretch. Improvements in analyzing myocardial strips can help future heart research to minimize heart-related problems.

Keywords: heart, cardiac, myocardium