BIO

Greetings! I'm Sabrina Roman, a senior pursuing a major in Biomathematics at Florida State University. My fervent passion lies at the intersection of mathematics and medicine, where I aim to make a tangible impact on our world. Currently, my research focuses on exploring the arithmetic capabilities of individuals with Alzheimer's disease and meta-cognitive impairment. Beyond academia, I cherish moments spent with loved ones and have an affinity for discovering quaint coffee shops around town. Looking ahead, I envision a career in healthcare where I can merge my interests in mathematics and medicine, continuing to drive innovative research in both fields.

Arithmetic Skills in Patients with Mild Cognitive Impairment and Alzheimer's Disease - Literature Review

Abstract

Deficiencies in general arithmetic abilities are noted as an initial indicator of Alzheimer's disease (AD), although research findings vary regarding the specific affected abilities. Moreover, a comprehensive literature review documenting the progression of arithmetic skill changes from Mild Cognitive Impairment (MCI) to Alzheimer's disease is lacking. The objective of this study is to systematically review existing literature on the performance of individuals with MCI and AD in arithmetic skills, aiming to consolidate current knowledge and suggest potential avenues for future research. PRISMA guidelines were followed for the systematic literature search using Covidence software. Included literature focused on arithmetic skills in MCI and/or AD patients, while excluding articles on financial capabilities, comprehension of medical information, non-English papers, and case studies with minimal participants. Thirty-six articles discussing arithmetic skills in MCI and/or AD patients were identified through the search. Analysis revealed that within the MCI group, patients exhibited greater accuracy in addition compared to other operations. Regarding reaction time, MCI patients were slower than healthy controls (HC) only in division. No significant difference in accuracy in addition and multiplication was observed between AD patients and HC, while AD patients demonstrated lower accuracy in subtraction and division.

Keywords: Alzheimers, meta-analysis, literature review