BIO

My name is Adria Morales Santiago, and I am a freshman majoring in Biological Sciences. I am from Cuba, but I am currently residing in Naples, Florida. After I complete my undergraduate studies, I plan to pursue medical school with the goal of becoming a surgical oncologist. I want to become more involved in cancer research with a focus on the molecular and cellular processes. I am also interested in psychology, specifically how Alzheimer's Disease affects the lives of the older population. In my free time I enjoy reading, volunteering, and learning new languages.

Spatial Navigation Skills In Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) – A Meta-Analysis

Abstract

Abstract:
Background: Spatial disorientation emerges as a prominent early indicator of Alzheimer's Disease (AD), as emphasized in the 2018 study by Coughlan et al. Difficulties in spatial navigation frequently manifest in individuals with Mild Cognitive Impairment (MCI), a syndrome with a high probability of progressing to dementia. A prior meta-analysis demonstrated a significant difference (p < 0.05) in navigation skills between healthy cognitively older adults and individuals with MCI, with a standardized mean difference (SMD) of 0.88.
Methods: The present meta-analysis compares the results between the performance of older adults diagnosed with MCI and older adults diagnosed with AD. To accurately assess the magnitude of the effect size, the standardized mean difference (Hedge’s g) will be employed.
Results: Following our literature search, we identified 16 studies that fulfilled our inclusion criteria. We are currently in the midst of extracting data from these studies.

Keywords: Spatial navigation, Alzheimer's Disease, Mild-Cognitive Disorder