Research Symposium

22nd annual Undergraduate Research Symposium

Kyle Kraeher he/him Poster Session 4: 12:30 - 1:15/Poster #62


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BIO


Pre-Med student from Jupiter, Florida. Sports medicine has always been extremely interesting to me and has been a professional goal since middle school. This study covers the benefits of creatine supplementation towards glucose and lipid levels, this is significant because creatine can be potentially used as a therapeutic aid for its positive effects on glucose and lipid levels which is significantly cheaper than generic medicine for these problems.

The Effects of 4-Week Creatine Supplementation on Lipid Profiles in Older Adults

Authors: Kyle Kraeher, Holly Clarke
Student Major: Biology
Mentor: Holly Clarke
Mentor's Department: Department of Nutrition
Mentor's College: FSU
Co-Presenters: Victor Angel

Abstract


Aging can lead to the deterioration of a variety of physiological systems.
Older adults are at a higher risk of both hyperglycemia and dyslipidemia,
both of which can be further augmented by a poor diet and inactivity.
There is some evidence suggesting that creatine may potentially serve
as a therapeutic aid, eliciting positive effects upon blood glucose and
lipid levels. Therefore, creatine has been termed a potential
nutraceutical, capable of exerting promising effects upon common
pathologies the US population face today. The purpose of this research
was to determine the effects of four weeks of creatine supplementation
on lipids and blood glucose in healthy, older adults. Twelve adults
consumed creatine monohydrate (CM) and placebo for 4 weeks. Preand post supplementation, participants underwent a fasted venous blood
draw. Plasma levels of cholesterol (CHOL), high density lipoprotein
(HDL), triglycerides (TG), non-HDL cholesterol (nHDLc), low density
lipoprotein (LDL), very LDL (vLDL), and blood glucose (GLU) were then
analyzed using a Piccolo Xpress clinical chemistry analyzer. Results
were analyzed by 2x2 Repeated Measures ANOVA, with significance
accepted as p < 0.05. vLDL decreased in both groups on average – 2.46
mg/dL showing significant improvement in TG and GLU however there
were no significant changes following CM in LDL, HDL, nHDLc, or
CHOL. Due to the strong relationship between triglycerides and glucose
with CVD, the ability of creatine to reduce these suggests that creatine
may have the possibility to serve as an adjuvant therapy for the control of
TGs and glucose.

Keywords: Creatine Lipid Adults