UROP Research Mentor Project Submission Portal: Submission #555

Submission information
Submission Number: 555
Submission ID: 9046
Submission UUID: 27525ef8-857c-4518-8d5b-e924a40de6a8

Created: Wed, 08/23/2023 - 11:39 AM
Completed: Thu, 08/24/2023 - 05:13 PM
Changed: Thu, 10/05/2023 - 10:05 AM

Remote IP address: 69.254.161.249
Submitted by: Anonymous
Language: English

Is draft: No
Primary Research Mentor Name Caroline Menton
Research Mentor Preferred Pronouns She/Her
When potential research assistants are reaching out via email, what is your preferred honorific? Ms.
Contact Email (FSU Email if affiliated) cbm20bv@med.fsu.edu
Position Title Graduate Student
Faculty Advisor Name
Faculty Advisor's FSU Email
FSU College (if applicable) Medicine
FSU Department or Non-FSU Organization Affiliation Florida State University College of Medicine
Headshot (optional)
Research Assistant Supervisor (if different from above)
Research Assistant Supervisor Preferred Pronouns
Research Assistant Supervisor Preferred Honorific?
Contact Email (FSU Email if affiliated)
Name of Other Faculty/Collaborator(s) (if applicable)
Other Faculty/Collaborator(s) Preferred Pronouns
Other Faculty/Collaborator(s) Preferred Honorific?
Contact Email (FSU Email if affiliated)
Title of the Project The Effects of Caffeine on Motor Performance in Parkinson's Disease
Project Keywords Caffeine, Neurodegenerative Disease, Parkinson's Disease
Are you currently looking for research assistants? No
Number of Research Assistants Needed 1
Relevant Research Assistant Major(s) Neuroscience, biology, chemistry, pre-med, IMS
Project Location: On FSU Main Campus
If the project location is off campus, does the research assistant(s) need to provide their own transportation?
Please select the choice that most accurately describes your expectations for the research assistant(s): Partially Remote
Approximately how many hours a week would the research assistant(s) need to work? 5
Roughly what time frame do you expect research assistant(s) to work? Flexible schedule (Combination of business and outside of business. TBD between student and research mentor.)
Overall Research Project Description The purpose of this study is to acquire data on the gross and fine motor function of patients with Parkinson’s Disease when they are at peak dose of primary therapy and compare this with data collected at peak dose with a caffeine adjuvant of ~3mg/kg. The treatment standard for PD is dopamine replacement therapy (e.g. levodopa) to improve quality of life and reduce falls risk. Over time, patients may require increasing dose and frequency of levodopa therapy, which can precipitate side effects (e.g. dyskinesia) and hasten the rate of disease progression. To prevent this, researchers have been investigating adjuvants and supplements that can improve peak performance on levodopa. While the neuroprotective effects of caffeine are well established in the literature, the acute effects of caffeine on motor performance have not been sufficiently evaluated. In this study, we will examine the acute effects of caffeine as an adjuvant therapy during peak dose of primary therapy in Parkinson’s patients. Detailed analysis of the physical effects of caffeine is necessary to determine what, if any, role caffeine can play in the treatment and management of PD. This study is a double-blinded crossover study using randomized placebo-intervention to assess the effect of caffeine on motor performance.
Research Tasks Literature review, Data Analysis, write-up
Skills that research assistant(s) may need: Recommend - statistics
Mentoring Philosophy My goal is for this to be a meaningful experience for everyone involved. I am hoping to share my enthusiasm for this project (and for research in general), and to work together to make something awesome! This is a great opportunity for students to learn about clinical research, and I want to create an environment that encourages students to become proficient researchers and creative thinkers.
Please provide a link to your publications, a video clip, or a website for your research project (if applicable):
Please add any additional information here (if applicable): You can view the IRB for this project on the RAMP IRB page (STUDY00001144). Feel free to email me with additional questions.
Mentor Handbook, FAQs, and Communication Yes
UROP Performance Evaluation Yes
Materials Grant Yes
UROP Poster Presentation Yes
Faculty Advisor Confirmation
Are you interested in attending in a UROP Research Mentor Workshop Series? No
Year 2023
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