UROP Research Mentor Project Submission Portal: Submission #410 | Center for Undergraduate Research and Academic Engagement

Submission information

Submission Number: 410

Submission ID: 8321

Submission UUID: 8cd3c86a-4150-4106-ab4f-12a4695dbb44

Submission URI: /urop-research-mentor-project-submission-portal

Submission Update: /urop-research-mentor-project-submission-portal?token=dXj7Hyi3xzKQ2XrQOZdDlqrSCD6gFaoCXdcByWu55Fc

Created: Thu, 08/10/2023 - 05:11 PM

Completed: Thu, 08/10/2023 - 05:11 PM

Changed: Thu, 10/19/2023 - 10:06 AM

Remote IP address: 217.180.196.37

Submitted by: Anonymous

Language: English

Is draft: No

Webform: UROP Project Proposal Portal

Submitted to: UROP Research Mentor Project Submission Portal

Research Mentor Information

Primary Research Mentor Name Daniel Machin

Research Mentor Preferred Pronouns {Empty}

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Contact Email (FSU Email if affiliated) dmachin@fsu.edu

Position Title Faculty

FSU College (if applicable) Health and Human Sciences

FSU Department or Non-FSU Organization Affiliation FSU

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Additional Research Mentor(s)

Research Assistant Supervisor (if different from above) {Empty}

Research Assistant Supervisor Preferred Pronouns {Empty}

Research Assistant Supervisor Preferred Honorific? {Empty}

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Name of Other Faculty/Collaborator(s) (if applicable) {Empty}

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Overall Project Details

Title of the Project Age-Related Arterial Dysfunction

Project Keywords Arteries endothelium blood pressure Down syndrome

Are you currently looking for research assistants? No

Number of Research Assistants Needed 6

Relevant Research Assistant Major(s) Open to all majors

Project Location: On FSU Main Campus

If the project location is off campus, does the research assistant(s) need to provide their own transportation? {Empty}

Please select the choice that most accurately describes your expectations for the research assistant(s): In-person

Approximately how many hours a week would the research assistant(s) need to work? 10 hours/week

Roughly what time frame do you expect research assistant(s) to work? During business hours

Overall Research Project Description My research focuses on cardiovascular physiology and the influence of aging and lifestyle on the development of cardiovascular disease. There are a number of age- and lifestyle-related changes in the structural and functional properties of arteries that result in impaired vascular function, elevated blood pressure, and contribute to cardiovascular disease risk. I study the effects of intervention, particularly exercise and dietary, on restoration of vascular function and reductions in blood pressure. Additionally, I study physiological and molecular mechanisms responsible for changes in vascular function and blood pressure with aging and following intervention, as well as in Down syndrome. We have a novel mouse model of Down syndrome, TcMAC21 mouse, to address these research questions.

Research Tasks data collection, data analysis, mouse handling, general lab skills

Skills that research assistant(s) may need: No experience is required, but students must be willing to handle mice.

Mentoring Philosophy My primary goal as a mentor is to provide a foundation and structure for students to develop into independent researchers. The cornerstone of a successful mentor-mentee relationship is to develop a strategy that aligns the research interests, career goals, and innovative ideas of each mentee with my goals as a researcher. Each mentee is different and some may come from diverse ethnic and cultural backgrounds. Therefore, aligning expectations must be done on an individual basis to account for these factors. I prefer to be hands off and allow each student to make mistakes, but also to learn from mistakes. To become a good scientist you must focus on the details and be able to recognize when an observation is an error vs. an actual finding.

Please provide a link to your publications, a video clip, or a website for your research project (if applicable): https://healthandhumansciences.fsu.edu/departments/nip/faculty-staff/daniel-machin/

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UROP Program Elements

Mentor Handbook, FAQs, and Communication Yes

UROP Performance Evaluation Yes

Materials Grant Yes

UROP Poster Presentation Yes

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Year 2023

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