Research Mentor Information
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Primary Research Mentor Name: Daniel Machin
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Contact Email (FSU Email if affiliated): dmachin@fsu.edu
Position Title: Faculty
FSU College (if applicable): Health and Human Sciences
FSU Department or Non-FSU Organization Affiliation: FSU
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Additional Research Mentor(s)
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Overall Project Details
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Title of the Project: Age-Related Arterial Dysfunction
Project Keywords: Arteries endothelium blood pressure Down syndrome
Are you currently looking for research assistants?: No
Number of Research Assistants Needed : 6
Relevant Research Assistant Major(s):
Open to all majors

Project Location:: On FSU Main Campus
If the project location is off campus, does the research assistant(s) need to provide their own transportation?: {Empty}
Please select the choice that most accurately describes your expectations for the research assistant(s):: In-person
Approximately how many hours a week would the research assistant(s) need to work?: 10 hours/week
Roughly what time frame do you expect research assistant(s) to work?: During business hours
Overall Research Project Description:
My research focuses on cardiovascular physiology and the influence of aging and lifestyle on the development of cardiovascular disease. There are a number of age- and lifestyle-related changes in the structural and functional properties of arteries that result in impaired vascular function, elevated blood pressure, and contribute to cardiovascular disease risk. I study the effects of intervention, particularly exercise and dietary, on restoration of vascular function and reductions in blood pressure. Additionally, I study physiological and molecular mechanisms responsible for changes in vascular function and blood pressure with aging and following intervention, as well as in Down syndrome. We have a novel mouse model of Down syndrome, TcMAC21 mouse, to address these research questions. 

Research Tasks:
data collection, data analysis, mouse handling, general lab skills

Skills that research assistant(s) may need::
No experience is required, but students must be willing to handle mice.

Mentoring Philosophy:
My primary goal as a mentor is to provide a foundation and structure for students to develop into independent researchers. The cornerstone of a successful mentor-mentee relationship is to develop a strategy that aligns the research interests, career goals, and innovative ideas of each mentee with my goals as a researcher. Each mentee is different and some may come from diverse ethnic and cultural backgrounds. Therefore, aligning expectations must be done on an individual basis to account for these factors. I prefer to be hands off and allow each student to make mistakes, but also to learn from mistakes. To become a good scientist you must focus on the details and be able to recognize when an observation is an error vs. an actual finding.

Please provide a link to your publications, a video clip, or a website for your research project (if applicable):: https://healthandhumansciences.fsu.edu/departments/nip/faculty-staff/daniel-machin/
Please add any additional information here (if applicable)::
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UROP Program Elements
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Mentor Handbook, FAQs, and Communication: Yes
UROP Performance Evaluation: Yes
Materials Grant: Yes
UROP Poster Presentation: Yes

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Year: 2023
update url: https://cre.fsu.edu/urop-research-mentor-project-submission-portal?token=dXj7Hyi3xzKQ2XrQOZdDlqrSCD6gFaoCXdcByWu55Fc