BIO

My name is Jackzyri Torres, I am a freshman here at Florida State University. I am from Miami, Florida, but I am 100% Nicaraguense. With my education from Florida State, I aim to receive a masters in Social Work and eventually become a licensed clinical social worker. Aside from this project, I am interested in researching Hispanic populations, along with those who have been incarcerated.

Spatial Navigation Skills in Alzheimer's Disease- A Meta- Analysis

Abstract

Background: Dementia greatly impacts various individuals. A common form of dementia is Alzheimer's Disease (AD). One of the earliest symptoms noted in AD is spatial disorientation. Spatial disorientation occurs when an individual cannot determine their accurate body position, altitude, and motion in relation to their surroundings. In a prior meta-analysis that examined spatial navigation skills in individuals with Mild Cognitive Impairment (MCI), it was observed that they diverged from cognitively healthy older adults by a standardized mean difference of 0.9. MCI represents a state between cognitively healthy aging and dementia.

Methods: In this meta-analysis, the objective is to evaluate the degree to which individuals with AD exhibit cognitive underperformance compared to cognitively healthy older individuals in spatial navigation tasks. Hedge’s g, a standardized mean difference, serves as the measure of effect size in this assessment. Notably, characteristics of articles such as title, year of publication, country of study, and authors are considered along with demographic variables (education, age, and gender), way of test administration (real-world, virtual reality), AD criteria, and type of measure (time/accuracy)..

Results: The present dataset comprises 48 effect sizes from 21 studies, involving a total of 483 participants (212 AD, 271 healthy older adults). The overall findings indicate a statistically significant difference (p = 0.05) in navigation skills, with healthy older adults exhibiting significantly better performance compared to individuals with AD, as evidenced by the standardized mean difference (SMD) of 1.3.

Keywords: Alzheimer's, Spatial navigation, Meta Analysis